Most antidepressants work by blocking the liver’s MAO enzyme so that the brain assimilates serotonin and dopamine. In the ayahuasca vine, this substance, which inhibits the MAO enzyme, is natural and is called MAOI.
When a person takes antidepressants, they should inform the taita, especially because sometimes some taitas prepare ayahuasca with other plants, such as chiricaspi, which has an active ingredient datura and scopolamine. These don’t interact well with synthetic MAO, and can cause the patient to experience a traumatic journey.
However, when the taita already knows that the person is taking antidepressants, he knows that their body is more receptive to DMT, and he knows that his dose and the type of ayahuasca medicine he is going to serve is different because, and this is key, he has prepared this specific medicine.
He knows perfectly well how to administer it.
Many supposed taitas in Europe and even in Latin America buy ayahuasca by the liter and have had unfortunate accidents with patients taking antidepressants because the taitas themselves do not know they are serving.
So, the person who wants to take ayahuasca and also takes antidepressants should:
– suspend use of the medication a few days before (or at least one day before) the session/retreat and should be constantly hydrating.
– if you have the time and access, you should start taking three Omega 3+6+9 tablets a day (one tablet usually includes the 3 omegas; you take one tablet with every meal of the day) from one week before the session. This raises the levels of serotonin and dopamine in the brain and helps clear the liver of synthetic MAO.
– during retreats/ceremonies DO NOT take medication
– after the retreat, you should continue with the Omega treatment
If you can’t access the Omega tablets, or don’t have time, the most important thing is to hydrate and drink water from plants, like dandelion root.